Nature has programmNature has programmed us to age. This is known as ‘programmed senescence.’ Humans and animals have a biological clock that determines our birth and ability to grow, reproduce and die. At least, this is how it has been understood for years with an approach that did not look beyond resignation.
But this reality is increasingly questionable if we consider that in the last hundred years, we have managed to prolong But this reality is increasingly questionable if we consider that we have managed, in the last hundred years, to prolong our lives as never before in recorded history. And to achieve this, it has not been necessary to make a pact with the devil as Faust, and Dorian Gray did. In 1900, women’s life expectancy was 35 years, and men’s was less than 33 years. Today, women live an average of 86 years and men 83.
There is a consensus in the medical and scientific community that we are beginning a genetic revolution that will lead us to live an average of 122 years during this century. Who is behind this revolution? Many Silicon Valley millionaires aspire to immortality. Sergei Brin, a co-founder of Google, has invested 838 million euros in a laboratory studying ageing and how to cure it.
Today we are already able to know our rate of ageing with a blood test. We also know that the amount of food we eat and the exercise we do have an immediate effect on our ageing process.
Aging begins at the age of 34
Thanks to a study developed by researchers at Stanford University, we now know the three stages of aging in a person’s life. This research reveals, for the first time, that the aging process begins at age 34. The second stage occurs Thanks to a study by researchers at Stanford University, we now know the three stages of ageing in a person’s life. This research reveals, for the first time, that the ageing process begins at the age of 34. The second stage occurs at the age of 60, and the third stage starts at the age of 78. How was this conclusion reached? Benoit Olivier Lehallier, lead author of the study, and his colleagues have created what they call the “proteomic clock,” designed to calculate biological age by studying 373 proteins that circulate in the blood. The trial involved 4,263 people between the ages of 18 and 95. How many signs show ageing? According to Stanford’s study, there are five. First, metabolism slows down; second, the bone structure weakens; third, it becomes increasingly difficult to remember past actions; fourth, sleep patterns are disrupted; and finally, by the age of 78, organ decline and cognitive capacity suffer a rapid and irreversible decline.
Now let’s try to define aging. What does it consist of?
According to David Sinclair, a genetics professor at Harvard Medical School and one of Time magazine’s 100 most important people in the world, ageing is a disease that damages the body to the extent that it undermines its proper functioning. For the author of the book “Lengthen your life expectancy: How science helps us to control, slow down and reverse the ageing process” (Grijalbo), ageing is the main cause of most of the diseases we suffer throughout our lives, and which end up causing our death irremediably. Treating ageing as a disease is not one of David Sinclair’s inventions. The World Health Organization (WHO) has also included it in its official list of chronic non-communicable diseases. We are referring to those ailments that arise between the ages of 30 and 40, such as diabetes, cancer, osteopenia, and neurodegenerative diseases, among others, and which we will all suffer from sooner or later.
Aging depends on two factors: genetics – what is written in our genes – and epigenetics. Researchers such as David Sinclair and Manel Esteller, director of the Epigenetics and Cancer Biology Program at the Bellvitge Biomedical Research Institute (Barcelona), have shown that the latter factor is vital because it explains how genes relate to the Ageing depends on two factors: genetics – what is written in our genes – and epigenetics. Researchers such as David Sinclair and Manel Esteller, director of the Epigenetics and Cancer Biology Program at the Bellvitge Biomedical Research Institute (Barcelona), have shown that the latter factor is key because it explains how genes relate to the environment, how we treat our lives and our everyday habits. This includes nutrition, whether we exercise or whether we sleep too much or too little. Also, whether we smoke or drink alcohol. Other determining factors would be anxiety, stress, and pollution.
If we take care of our epigenetics, we can delay ageing. Biochemist and 2009 Nobel Laureate in Medicine, Elisabeth Blackburn, has shown in several studies that if we have good nutrition, exercise, and control stress, it is possible to delay ageing and maintain the body’s vitality for longer.
How to delay the signs of aging
1. Sleep is essential
In the short term, it will help keep your cognitive skills sharp, as well as your creativity and attention span. In the long term, lack of sleep is linked to heart disease, Alzheimer’s, and hypertension. It is vital to allow your body to reboot while you are in bed.
2. Protect your skin
Moisturisers and sunscreens prevent the appearance of wrinkles and reduce the risk of skin cancer. According to the Skin Cancer Foundation, if you apply anti-UV sunscreen, you will reduce your chances of getting melanoma by up to 50%.
3. Engage intense exercise
This has been proven by a Mayo Clinic study. When you lift weights or do other intense activities, you activate genes that shut down over the years that affect the mitochondria’s ability to generate the chemical energy needed to activate the cell’s biochemical reactions. According to Mayo Clinic researchers, “lifting weights helps maintain bone density, better control your weight and improve your body’s metabolism.”
4. Avoid smoking
There is a direct link between smoking and premature ageing. The carbon monoxide in tobacco adds to haemoglobin and reduces the rate of oxygen in the blood. In addition, smoking stimulates metalloproteinase activity, which accelerates the degradation of elastic fibres, collagen, and dermal proteoglycans.
5. Take food supplements when you consider them necessary
ThThere are many food supplements on the market aimed at delaying ageing, and new solutions may emerge in the future. For example, ingredients such as collagen, hyaluronic acid, and MSM help to keep the skin firmer and more hydrated. Antioxidants such as vitamin C, vitamin E or Resveratrol protect cells from oxidative stress, not forgetting coenzyme Q10, a molecule that provides energy to our cells and whose presence in the body decreases with age. VERY IMPORTANT: these solutions should never replace a healthy, balanced diet.
6. Trans-Resveratrol by Zenement
IIt is our main active ingredient for slowing down the effects of ageing. Resveratrol is a natural polyphenol contained in many plants such as grapes, blueberries, and blackberries… At Zenement, we extract this polyphenol, from the root of Polygonum cuspidatum, a herbaceous species used in Chinese medicine, with a purity level of 98%. It was in the 1990s that plant extracts containing Resveratrol began to be isolated to study its properties with scientific precision.
7. Why take Resveratrol?
“Every day, there is more and more research on the mechanisms of aging and the health problems it causes in the “Every day, more and more research is being carried out to study ageing mechanisms and the health problems it causes in the organism. The quest for healthy ageing has led to the discovery of active ingredients with anti-ageing properties, and one example is Resveratrol, or more specifically, Trans-Resveratrol (the bioactive form). It has been found that this molecule is capable of activating sirtuins, proteins related to cell survival, which translates into a protective effect on cells. It is an effect similar to that obtained with intermittent fasting, a practice that has gained popularity in recent times due to the obvious benefits it provides,” explains Clara Babot, a pharmacist, Ph.D. in chemistry, and member of the Zenement team. She goes on to say: “In our formula, we combine 500 mg of Trans-Resveratrol with other active ingredients to increase its efficacy and bioavailability. We use quercetin which, combined with Resveratrol, has been shown to create a synergistic effect on sirtuin activation. Not forgetting nicotinamide as an active precursor of the coenzyme NAD+ (necessary for sirtuins to carry out their metabolic action) and piperine which increases the absorption of all the formula’s components”.
How much do I have to take?
Single-dose studies suggest taking between 450 and 500 milligrams of Resveratrol per day.
OUR ANTIAGING PRODUCTS